Department of Pathogen Biology

Yisong Wang

Associate Professor/Master’s Supervisor | Department： Department of Microbiology

Email：yswang@ccmu.edu.cn

010-83950439 (Lab)

Address：No.10, Xitoutiao, You’anmenwai, Beijing

Research Area：Our research interest is in the relationship between herpes virus infection and major brain diseases. The herpes virus family has neurotropic characteristics, and congenital infections can lead to neurodevelopmental disorders, which may result in serious consequences for immunocompromised patients. The main focus is on the role of herpes virus infection in Rasmussen encephalitis and brain tumors.

Education
2004-2007: Ph.D. in Neurobiology, Capital Medical University, Beijing, China
2001-2004: M.Sc. in Neurobiology, Capital Medical University, Beijing, China

Work Experience
2025-present: Associate Professor, School of Basic Medical Sciences, Capital Medical University, China
2010-2011: Postdoctoral Researcher, University of Calgary, Canada
2007-2024: Lecturer, School of Basic Medical Sciences, Capital Medical University, China

*：Co-first author; #：Co-corresponding author

[1] Song Z R*, Yang Y L*, Zhou Y, Liu L B, Xue F Y, Liu L S, Gao N, Fan D Y, Wang Y S#, An J#, Wang P G#. The slow progression of Japanese encephalitis in aged mice is likely associated to B cell recruitment in the brain [J]. Virologica Sinica, 2025, Jun 3:S1995-820X(25)00071-9.

[2] Wang Y S*, Liu D*, Wang X*, Luo Q L, Ding L, Fan D Y, Cai Q L, Tang C Y, Yang W, Guan Y G, Li T F, Wang P G#, Luan G M#, An J#. Rasmussen's encephalitis is characterized by relatively lower production of IFN-beta and activated cytotoxic T cell upon herpes viruses infection [J]. Journal of neuroinflammation, 2022, 19(1): 70.

[3] Wang Y S, Luo Q L, Guan Y G, Fan D Y, Luan G M#, Jing A#. HCMV infection and IFITM3 rs12252 are associated with Rasmussen's encephalitis disease progression [J]. Annals of clinical and translational neurology, 2021, 8(3): 558-570.

[4] Luo Q*, Wang Y*, Fan D, Wang S, Wang P#, An J#. Prion Protein Expression is Correlated with Glioma Grades [J]. Virologica Sinica, 2020, 35(4): 490-493.

[5] Zhang Y*, Wang Y*, Chen S, Chen S, Guan Y, Liu C, Li T, Luan G#, An J#. Expression of human cytomegalovirus components in the brain tissues of patients with Rasmussen's encephalitis [J]. Virologica Sinica, 2017, 32(2): 115-121.

[6] Xing Y*, Wang Y*, Wang S, Wang X, Fan D, Zhou D#, An J#. Human cytomegalovirus infection contributes to glioma disease progression via upregulating endocan expression [J]. Translational research : the journal of laboratory and clinical medicine, 2016, 177(113-126.

[7] Miao Y*, Zong M*, Jiang T, Yuan X, Guan S, Wang Y#, Zhou D#. A comparative analysis of ESM-1 and vascular endothelial cell marker (CD34/CD105) expression on pituitary adenoma invasion [J]. Pituitary, 2016, 19(2): 194-201.

[8] Chen S*, Chen S*, Guan Y, Zhang Y, Qi X, An J, Wang Y#, Luan G#. Elevated expression of human papillomavirus antigen in brain tissue of patients with Rasmussen's encephalitis [J]. Epilepsy research, 2016, 126(119-125).