Xuelin Zhou

*：Co-first author; #：Co-corresponding author

[1]Xinyi Tong^*, Yining Qiang^*, Mingchang Cheng, Yan Tie, Zhihui Sun, Yi Ma, Yushan Wu, Liping Xu, Pingxiang Xu, Xiaorong Li, Ming Xue, Xuelin Zhou. Multi-Omics analysis revealed the therapeutic mechanisms of Gegen (Puerariae lobatae Radix) water extract against ischemia-induced bladder overactivity through the inhibition of epoxide hydrolase 2. Phytotherapy research . 2025, 39(8): 3813-3828. DOI: 10.1002/ptr.8076.

[2]Jiawei Wang^*, Qichao Hu^*, Jianying Wang^*, Liwei Lang, Shizhang Wei, Haotian Li, Manyi Jing, Xiao Ma^#, Yanling Zhao^#, Xuelin Zhou^#. Role of gut microbiota and fecal metabolites in the protective effect of soybean pulp-rich diet against estrogen-induced cholestasis in rats. Current Research in Food Science . 2025, 10(6):100990. DOI: 10.1016/j.crfs.2025.100990.

[3]Mingchang Cheng, Yining Qiang, Yushan Wu, Xinyi Tong, Yan Tie, Zhihui Sun, Shenghan Guan, Liping Xu, Pingxiang Xu, Xiaorong Li, Ming Xue, Xuelin Zhou. Multi-omic approaches provide insights into the molecular mechanisms of Sojae semen germinatum water extract against overactive bladder. Food Research International . 2024, 175: 113746. DOI:  10.1016/j.foodres.2023.113746.

[4]Yan Tie, Zhihui Sun, Xinyi Tong, Mingchang Cheng, Yushan Wu, Zhilong Shi, Pingxiang Xu, Ming Xue, Liping Xu^#, Xuelin Zhou^#. Multi-Omic analysis revealed the therapeutic mechanisms of Alpinia Oxyphylla Fructus water extract against bladder overactivity in spontaneously hypertensive rats. Phytomedicine , 2024, 123: 155154. DOI: 10.1016/j.phymed.2023.155154.

[5]Yi Wu^*, Yi Ma*, Qiang Li, Jing Li, Di Zhang, Yuxin Zhang, Yue Li, Xiaorong Li, Pingxiang Xu, Lu Bai, Xuelin Zhou^#, Ming Xue^#. Multi-omics analysis reveals phenylalanine enhance mitochondrial function and hypoxic endurance via LKB1/AMPK activation. Journal of Translational Medicine . 2024, 22: 920. DOI: 10.1186/s12967-024-05696-5.

[6]Zhihui Sun, Yan Tie, Xinyi Tong, Mingchang Cheng, Yushan Wu, Pingxiang Xu, Ming Xue, Liping Xu^#, Xuelin Zhou^#. Multi-omics approaches revealed the therapeutic mechanisms of Suo-Quan-Wan for treating overactive bladder in spontaneously hypertensive rats. Journal of Ethnopharmacology . 2024, 318(Pt B): 117066. DOI: 10.1016/j.jep.2023.117066.

[7]Qiang Li, Zhengchao Xia, Yi Wu, Yi Ma, Di Zhang, Sihan Wang, Jingxin Fan, Pingxiang Xu, Xiaorong Li, Lu Bai, Xuelin Zhou^#, Ming Xue^#. Lysophospholipid acyltransferase-mediated formation of saturated glycerophospholipids maintained cell membrane integrity for hypoxic adaptation. FEBS Journal . 2024, 291(14): 3191-3210. DOI: 10.1111/febs.17132.

[8]Yan Tie^*, Jihan Liu^*, Yushan Wu^*, Yining Qiang, Ge’Er Cai’Li, Pingxiang Xu, Ming Xue, Liping Xu, Xiaorong Li^#, Xuelin Zhou^#. A Dataset for Constructing the Network Pharmacology of Overactive Bladder and Its Application to Reveal the Potential Therapeutic Targets of Rhyncholphylline. Pharmaceuticals . 2024, 17, 1253. DOI: 10.3390/ph17101253.

[9]Jiawei Wang, Jianxia Wen, Xiao Ma, Ju Yang, Zhao Zhang, Shuying Xie, Shizhang Wei, Manyi Jing, Haotian Li, Liwei Lang, Xuelin Zhou^#, Yanling Zhao^#. Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics. European Journal of Pharmacology . 2022, 935: 175331. DOI: 10.1016/j.ejphar.2022.175331.

Honors and Awards:

2024, 1^st prize, Science and Technology Award, China Association of Chinese Medicine (12/15)

2021, 3^rd prize, China Medical Science Award, Chinese Medical Association (2/8)

①BMC Complementary Medicine and Therapies, Editorial board Member
②Dose-response, Editorial board Member
③Journal of Pharmaceutical Analysis, Youth editorial board Member
④Advances in Urology, Academic editor
⑤China Pharmacology Society, Committees of Analytical Pharmacology / DMPK / Biochemical Pharmacology, Youth committee member
⑥Beijing Pharmacology Society, DMPK committee member