Department of Physiology and Pathophysiology

Xiaoyan Feng

Associate Professor/Master's Supervisor | Department：Department of Physiology and Pathophysiology

Email： fengxy@ccmu.edu.cn

010-83950475 (lab)

Address：No.10, Xitoutiao, You’anmenwai, Beijing

Research Area：Brain-Gut Axis Regulation of Mucosal Secretion, Absorption, and Barrier Function.

Education
2004-2009: Ph.D. in Physiology, School of Basic Medical Science,Capital Medical University, China
2003-2008: M.D. in Clinical Medicine, Tianjin Medical University, China

Work Experience
2021-present: Associate Professor, School of Basic Medical Sciences, Capital Medical University, China
2013-2020: Lecture, School of Basic Medical Sciences, Capital Medical University, China

*：Co-first author; #：Co-corresponding author

1.Xinxin Wen*, Xiaoyan Feng*, Fang Xin*, Rui An*, Huanwei Huang, Liyuan Mao, Ping Liu, Jin Zhang, Haixia Huang^#, Xicheng Liu^#, Wei Wang^#. B.vulgatus Ameliorates High-Fat Diet-induced Obesity through Modulating Intestinal Serotonin Synthesis and Lipid Absorption in Mice. Gut Microbes. 2024, 16(1), 2423040.

2.Jing-Ting Yan, Yin-zhe Zhu, Liang Liang, Xiao-Yan Feng^#. NE-activated β2-AR/β-arrestin 2/Src pathway mediates duodenal hyperpermeability induced by water-immersion restraint stress. American Journal of Physiology-Cell Physiology. 2023, 324: C133–C141.

3.Jing-Ting Yan, Xiao-Yu Liu, Jing-Hua Liu, Guang-Wen Li, Li-Fei Zheng, Xiao-Li Zhang, Yue Zhang, Xiao-Yan Feng^#, Jin-Xia Zhu^#. Reduced acetylcholine and elevated muscarinic receptor 2 in duodenal mucosa contribute to the impairment of mucus secretion in 6-hydroxydopamine-induced Parkinson’s disease rats. Cell and Tissue Research. 2021, 386(2), 249-260.

4.Feng XY, Yan JT, Li GW, Liu JH, Fan RF, Li SC, Zheng LF, Zhang Y, Zhu JX^#. Source of dopamine in gastric juice and luminal dopamine-induced duodenal bicarbonate secretion via apical dopamine D₂ receptors. British Journal of Pharmacology. 2020, 177(14):3258-3272.

5.Feng XY, Yan JT, Zhang XL, Zhu JX. Gastrointestinal non-motor dysfunction in Parkinson’s disease rats with 6-hydroxydopamine. Physiological Research. 2019, 68(2):295-303.

6.Feng XY, Zhang DN, Wang YA, Fan RF, Hong F, Zhang Y, Li Y^#, Zhu JX^#. Dopamine enhances duodenal epithelial permeability via the dopamine D5 receptor in rodent. ACTA Physiologica (Oxf). 2017, 220(1):113-123.

7.Feng XY, Li Y, Li LS, Li XF, Zheng LF, Zhang XL, Fan RF, Song J, Hong F, Zhang Y, Zhu JX^#. Dopamine D1 receptors mediate dopamine-induced duodenal epithelial ion transport in rats. Translational Research. 2013, 161(6):486-494.

Honors and Awards:

1.2025 Bronze Award Mentor, National Graduate Student Academic Innovation and Achievement Transformation Competition

2.2024 Capital Medical University Young Faculty Teaching Award

3.2021 Distinct Poster Award at the 16th National Outstanding Youth Physiology Conference