Department of Physiology and Pathophysiology

Baoqi Yu

Associate professor/doctoral supervisor | Department：Department of Physiology and Pathophysiology

Email：baoqiyu@ccmu.edu.cn

Address：No.10, Xitoutiao, You’anmenwai, Beijing

Research Area：The Yu laboratory mainly study the cardiovascular pathophysiology, focuses on stem cells and vascular remodeling diseases, exploring their pathological mechanisms.

Education
2012-2016: Ph.D. in Medical Engineering, School of Engineering and Materials Science, Queen Mary University of London, UK
2009-2012: Master in Pathophysiology, Institute of Cardiovascular Medicine, Peking University, China
2004-2009: B.S. Clinical Medicine, Guangzhou Medical University, China

Work Experience
2018-present: Associate professor, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, China
2017-2018: Postdoctoral Researcher, Guangdong Provincial People's Hospital, China

*：Co-first author; #：Co-corresponding author

1. Gao Q, Xu Q, Cao X, Xu X, Xu Q, Zhang C, Yu B. Precision Ultrasound-guided Stem Cell Delivery for Vascular Repair in Aortic Diseases. J Vis Exp. 2025 Jun 20;(220). DOI: 10.3791/68433

2. Cao X*, Jia J*, Gao Q*, Tao J, Wei M, Song Y, Wu H, Jiao S, Zhu X, Zhang X, Fu Y, Wang Y, Du J, Xu Q#, Qu A# and Yu B#. Elevated Dickkopf 3 Promotes Abdominal Aortic Aneurysm Formation via Modulated Phenotype Switch of Vascular Smooth Muscle Cells, Research, 2025 (accepted)

3. Qu Y, Wang A, Long C, Gao Q, Yu B. Senescence in cardiovascular diseases: Insights

into metabolic dysfunction in vascular cells. Global Transl Med. 2024:3(4):4619. DOI: 10.36922/gtm.4619

4. Zhao N*, Yu X*, Zhu X, Song Y, Gao F, Yu B#, Qu A#. Diabetes Mellitus to Accelerated Atherosclerosis: Shared Cellular and Molecular Mechanisms in Glucose and Lipid Metabolism. J Cardiovasc Transl Res. 2024 Feb;17(1):133-152. DOI: 10.1007/s12265-023-10470-x

5. Zhu X, Wang X, Jiao S, Liu Y, Shi L, Xu Q, Wang JJ, Chen Y, Zhang Q, Song Y, Wei M, Yu B, Fielitz J, Gonzalez F, Du J, Qu A. Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function. Acta Pharmacol Sin. 2023 Nov;44(11):2184-2200. DOI: 10.1038/s41401-023-01107-5.

6. Wang X, Zhu X, Shi L, Wang J, Xu Q, Yu B, Qu A. A time-series minimally invasive transverse aortic constriction mouse model for pressure overload-induced cardiac remodeling and heart failure. Front Cardiovasc Med. 2023 Feb 20:10:1110032. DOI: 10.3389/fcvm.2023.1110032.

7. Liu Y*, Duan Y*, Zhao N, Zhu X, Yu X, Jiao S, Song Y, Shi L, Ma Y, Wang X, Yu B, Qu A. Peroxisome Proliferator-Activated Receptor α Attenuates Hypertensive Vascular Remodeling by Protecting Vascular Smooth Muscle Cells from Angiotensin II-Induced ROS Production. Antioxidants (Basel).2022 Nov 30;11(12):2378. DOI: 10.3390/antiox11122378.

8. Tao J*, Cao X*, Yu B#, Qu A#. Vascular Stem/Progenitor Cells in Vessel Injury and Repair. Front Cardiovasc Med. 2022 Feb 10:9:845070. doi: 10.3389/fcvm.2022.845070.

9. Yu B, Wang X, Song Y, Xie G, Jiao S, Shi L, Cao X, Han X, Qu A. The role of hypoxia-inducible factors in cardiovascular diseases. Pharmacol Ther. 2022 Oct:238:108186. DOI: 10.1016/j.pharmthera.2022.108186.

10. Wang X, Zhu X, Jiao S, Qi D, Yu B, Xie G, Liu Y, Song Y, Xu Q, Xu Q, Gonzalez F, Du J, Wang X#, Qu A#. Cardiomyocyte peroxisome proliferator-activated receptor α is essential for energy metabolism and extracellular matrix homeostasis during pressure overload-induced cardiac remodeling. Acta Pharmacol Sin. 2022 May;43(5):1231-1242. DOI: 10.1038/s41401-021-00743-z.

Honors and Awards:

1. 2023 Capital Medical University Education and Teaching Awards, Young Faculty Teaching Award

2. 9 th Capital Medical University Young Faculty Teaching Competition (Basic Sciences Group), Second Prize

3. 13 th Basic Medical College Young Faculty Teaching Competition, Third Prize

4. Capital Medical University Science and Technology Awards, Natural Science Award (Second Prize)