*：Co-first author; #：Co-corresponding author
1.Yan Meng#, Cuiting Zheng, Xiyu Zhang, Zhenqiang Gao, Hongyu Chen, Xianmei Qi, Kai Li, Fangming Liu, Weiwei Deng, Yuting Wu, Jie Liu, Chen Chen, Chen Wang, Heng Zhao#, Hongbing Zhang#. xCT/Slc7a11 promotes pulmonary arterial hypertension by disrupting AMPKαsuppression of mTOR activation. Biochem Pharmacol. 2025 Jun: 236:116897.
2.Yaqi Xing, Zhenqiang Gao, Yunfei Bai, Wen Wang, Chen Chen, Yuanyuan Zheng, Yan Meng. Golgi protein 73 promotes LPS-induced cardiac dysfunction via mediating myocardial apoptosis and autophagy. J Cardiovasc Pharmacol. 2024 Jan 1;83(1):116-125.
3.Zhengqiong Gao, Cuiting Zheng, Yaqi Xing, Xiyu Zhang, Yunfei Bai, Chen Chen, Yuanyuan Zheng, Wen Wang, Hongbing Zhang, Yan Meng. Polo-like kinase 1 promotes sepsis-induced myocardial dysfunction. Int Immunopharmacol. 2023 Dec;125(Pt A):111074.
4.Rongrong Chen*, Hongfei Wang*, Cuiting Zheng*, Xiyu Zhang, Li Li, Shengwei Wang, Hongyu Chen, Jing Duan, Xian Zhou, Haiyong Peng, Jing Guo, Anchen Zhang, Feifei Li, Wang Wang, Yu Zhang, Jun Wang, Chen Wang, Yan Meng#, Xinling Du#, Hongbing Zhang#. Hypoxia promotes pulmonary hypertension through upregulation of PLK1. Respiratory Reasearch. 2023 Aug 19;24(1):204.
5.Xiyu Zhang, Cuiting Zheng, Zhenqiang Gao, Hongyu Chen, Kai Li, Lingling Wang, Yuanyuan Zheng, Chunjia Li, Hongjia Zhang, Ming Gong, Hongbing Zhang#, Yan Meng#. SLC7A11/xCT prevents cardiac hypertrophy by inhibiting ferroptosis. Cardiovasc Drug Ther. 2022 Jun;36(3):437-447.
6.Chen Chen, Xiyu Zhang, Cuiting Zheng, Zhenqiang Gao, Xi Jiang, Yunfei Bai, Yan Meng. Sulfasalazine exacerbates Angiotensin II induced cardiac remodeling by activating Akt signal pathway. Clin Exp Pharmacol Physiol. 2022 May 11. doi: 10.1111/1440-1681
7.Xiyu Zhang, Cuiting Zheng, Zhenqiang Gao, Lingling Wang, Chen Chen, Yuanyuan Zheng, Yan Meng. PKM2 promotes angiotensin‐II‐induced cardiac remodelling by activating TGF‐β/Smad2/3 and Jak2/Stat3 pathways through oxidative stress.J Cell Mol Med. 2021 Nov; 25(22): 10711–10723.
8.Yingxu Li, Bing Li, Xuechun Wang, Yan Meng, Lu Bai, Yuanyuan Zheng. Safe and efficient magnetic resonance imaging of acute myocardial infarction with gadolinium-doped carbon dots. Nanomedicine (Lond). 2020 Oct;15(24):2385-2398.
9.Chen Chen, Wei Jiang, Zongjian Liu, Fengwu Li, Jian Yang, Yanlong Zhao, Yuanyuan Ran, Yan Meng, Xunming Ji, Xiaokun Geng, Huishan Du#, Xiaoming Hu# .Splenic responses play an important role in remote ischemic preconditioning-mediated neuroprotection against stroke. J Neuroinflammation. 2018 May 28;15(1):167.
10.Jianhui Ma*, Yan Meng*, David J Kwiatkowski, Xinxin Chen, Haiyong Peng, Qian Sun, Xiaojun Zha, Fang Wang, YingWang, Yanling Jing, Shu Zhang, Rongrong Chen, Lianmei Wang, Erxi Wu, Guifang Cai, Izabela Malinowska-Kolodziej, Qi Liao, Yuqin Liu, Yi Zhao, Qiang Sun, Kaifeng Xu, Jianwu Dai, Jiahuai Han, Lizi Wu, Robert Chunhua Zhao, Huangxuan Shen, Hongbing Zhang. Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. J Clin Invest. 2010; 120(1): 103-14.
Honors and Awards:
1. The 11th Bilingual Teaching Skills Competition for Young Faculty, School of Basic Medical Sciences, Capital Medical University--Second Prize (2018)
2. The 1st National Young Faculty Pathology Teaching Competition--Excellence Award (2019)
Email：yanmeng_my@ccmu.edu.cn
010-83911700 (office)
Address： No.10, Xitoutiao, You’anmenwai, Beijing
Research Area：The Meng Laboratory investigates common diseases, such as hypertension and stroke, aiming to elucidate the regulatory mechanisms of the mTOR signaling pathway in disease pathogenesis and to explore targeted therapeutic strategies.