*:Co-first author; #:Co-corresponding author
1. Xie G, Gao L, Lu R, Tian L, Zheng T, Li X, Dang Y, Cole PA, Yu X#, Jiang H#, Chen Z#. Biochemical Analysis of PD-L1 ubiquitination by CRL3SPOP, ARIH1, and NEDD4 family ubiquitin ligases. Structure, 2025, 33(8): 1304-1313. DOI: 10.1016/j.str.2025.05.005
2. Jiang H, Miller BD, Viennet T, Kim H, Lee K, Athanari H, Cole PA. Protein Semisynthesis Reveals Plasticity in HECT E3 Ubiquitin Ligase Mechanisms. Nature Chemistry, 2024, 16: 1894-1905. DOI: 10.1038/s41557-024-01576-z
3. Jiang H, Chiang CY, Chen Z, Nathan S, D’Agostino G, Paulo JA, Song G, Zhu H, Gabelli SB, Cole PA. Enzymatic analysis of WWP2 E3 ubiquitin ligase using protein microarrays identifies autophagy-related substrates. Journal of Biological Chemistry, 2022, 298: 101854. DOI: 10.1016/j.jbc.2022.101854
4. Jiang H, Thomas SN, Chen Z, Chiang CY, Cole PA. Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases. Journal of Biological Chemistry, 2019, 294: 17421-17436. DOI: 10.1074/jbc.RA119.009211
5. Chen Z, Jiang H, Xu W, Li X, Dempsey DR, Zhang X, Devreotes P, Wolberger C, Amzel LM, Gabelli SB#, Cole PA#. A tunable brake for HECT ubiquitin ligases. Molecular Cell, 2017, 66: 345-357. DOI: 10.1016/j.molcel.2017.03.020
6. Jiang H, Dempsey DR, Cole PA. Ubiquitin ligase activities of WWP1 germline variants K740N and N745S. Biochemistry, 2021, 60: 357-364. DOI: 10.1021/acs.biochem.0c00869
7. Dempsey DR, Jiang H, Kalin JH, Chen Z, Cole PA. Site-specific protein labeling with N-hydroxysuccinimide-esters and the analysis of ubiquitin ligase mechanisms. Journal of the American Chemical Society, 2018, 140: 9374-9378. DOI: 10.1021/jacs.8b05098
8. Jiang H, D'Agostino GD, Cole PA, Dempsey DR. Selective protein N-terminal labeling with N-hydroxysuccinimide esters. Methods in Enzymology, 2020, 639: 333-353. DOI: 10.1016/bs.mie.2020.04.018
9. Jiang H, Cole PA. N‐Terminal Protein Labeling with N‐Hydroxysuccinimide Esters and Microscale Thermophoresis Measurements of Protein‐Protein Interactions Using Labeled Protein. Current Protocols, 2021, 1: e14. DOI: 10.1002/cpz1.14
10. Lee K*, Barone M*, Waterbury AL, Jiang H, Nam E, DuBois-Coyne SE, Whedon SD, Wang ZA, Caroli J, Neal K, Ibeabuchi B, Dhoondia Z, Kuroda MI, Liau BB, Beck S#, Mattevi A#, Cole PA#. Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature Chemical Biology, 2024. DOI: 10.1038/s41589-024-01671-9