Department of Neurobiology

Ying Zhang

Senior Lecturer | Department：Department of Neurobiology

Email： yingzhang@ccmu.edu.cn

010-83911461 (office)

Address：No.10, Xitoutiao, You’anmenwai, Beijing

Research Area：Cerebral ischemic/hypoxic injury and conditioning medicine.

Education
2006-2009: Ph.D. in Cell Biology, Capital Medical University, China
2001-2004: Master in Biochemistry and Molecular Biology, Tianjin Medical University, China
1996-2001: Medical Bachelor in Clinical Medicine, Tianjin Medical University, China
Work Experience
2015-present: Lecturer, Senior Lecturer, School of Basic Medical Sciences, Capital Medical University, China
2012-2015: Postdoctoral Researcher, Xuanwu Hospital, Capital Medical University, China
2004-2009: Research Associate, Xuanwu Hospital, Capital Medical University, China

*：Co-first author; #：Co-corresponding author

1. Yan Y, Wang Z, Liu X, Han S, Li J, Zhang Y#, Zhao L#. Identification of brain endothelial cell-specific genes and pathways in ischemic stroke by integrated bioinformatical analysis. Brain Circ. 2023; 9(4): 228-239. DOI: 10.4103/bc.bc_40_23

2. Zhang Y, Ma L, Yan Y, Zhao L, Han S, Wu D, Borlongan CV, Li J#, Ji X#. cPKCγ-Modulated Autophagy Contributes to Ischemic Preconditioning-Induced Neuroprotection in Mice with Ischemic Stroke via mTOR-ULK1 Pathway. Transl Stroke Res. 2023; 14(5): 790-801. DOI: 10.1007/s12975-022-01094-5

3. Zhang Y, Ma L, Ren C, Liu K, Tian X, Wu D, Ding Y, Li J, Borlongan CV, Ji X. Immediate remote ischemic postconditioning reduces cerebral damage in ischemic stroke mice by enhancing leptomeningeal collateral circulation. J Cell Physiol. 2019; 234(8): 12637-12645. DOI: 10.1002/jcp.27858

4. Zhang Y, Ma L, Su Y, Su L, Lan X, Wu D, Han S, Li J, Kvederis L, Corey S, Borlongan CV, Ji X. Hypoxia conditioning enhances neuroprotective effects of aged human bone marrow mesenchymal stem cell-derived conditioned medium against cerebral ischemia in vitro. Brain Res. 2019;1725:146432. DOI: 10.1016/j.brainres.2019.146432

5. Zhang Y, Ying G, Ren C, Jizhang Y, Brogan D, Liu Z, Li S, Ding Y, Borlongan CV, Zhang J#, Ji X#. Administration of human platelet-rich plasma reduces infarction volume and improves motor function in adult rats with focal ischemic stroke. Brain Res. 2015;1594: 267-273. DOI: 10.1016/j.brainres.2014.10.035

6. Zhang Y, Ren Z, Zou C, Wang S, Luo B, Li F, Liu S, Zhang YA. Insulin-producing cells from human pancreatic islet-derived progenitor cells following transplantation in mice. Cell Biol Int. 2011;35(5): 483-490. DOI: 10.1042/CBI20100152

7. Liu Y, Yuan Y, Yan Y, Wang R, Wang Z, Liu X, Zhang Y, Hua J, Wang Y, Zhao L. Mitochondrial pyruvate carrier 1 alleviates hypoxic-ischemic brain injury in rats. Life Sci. 2023; 325: 121686. DOI: 10.1016/j.lfs.2023.121686

8. Zheng J*, Wang Y*, Liu Y, Han S, Zhang Y, Luo Y, Yan Y, Li J#, Zhao L#. cPKCγ Deficiency Exacerbates Autophagy Impairment and Hyperphosphorylated Tau Buildup through the AMPK/mTOR Pathway in Mice with Type 1 Diabetes Mellitus. Neurosci Bull. 2022; 38(10): 1153-1169. DOI: 10.1007/s12264-022-00863-4

9. Wang Y, Liu Y, Yuan Y, Zhang Y, Luo Y, Han S, Yan Y, Wang Z, Liu X, Zhao L. Downregulation of mitochondrial pyruvate carrier 2 aggravates neuronal injury in the cortex following cerebral ischemia in rat. Brain Res Bull. 2022; 185: 193-202. DOI: 10.1016/j.brainresbull.2022.05.007

10. Wu D, Zhi X, Duan Y, Zhang M, An H, Wei W, Dong K, Zhang Y, Shi J, He X, Zhang J, Wu C, Meng R, Ding Y, Ji X#. Inflammatory cytokines are involved in dihydrocapsaicin (DHC) and regional cooling infusion (RCI)-induced neuroprotection in ischemic rat. Brain Res. 2019;1710:173-180. DOI: 10.1016/j.brainres.2018.12.033