Wei An

*：Co-first author; #：Co-corresponding author

1. Zhang C, Huang J, An W. Hepatic stimulator substance resists hepatic ischemia/reperfusion injury by regulating Drp1 translocation and activation. Hepatology . 2017 Dec;66(6):1989-2001.

2. Xiao WC, Zhang J, Chen SL, Shi YJ, Xiao F, An W. Alleviation of palmitic acid-induced endoplasmic reticulum stress by augmenter of liverregeneration through IP3R-controlled Ca2+ release. J Cell Physiol.  2018 Aug;233(8):6148-6157. 

3．Ai WL, Dong LY, Wang J, Li ZW, Wang X, Gao J, Wu Y, An W. Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell. Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3780-3791.

4. Liu LM , Xie P, Li W, Wu Y, An W. Augmenter of liver regeneration protects against ethanol-induced acute liver injury by promoting autophagy. Am J Pathol.  2019 Mar;189(3):552-567.

5. Wang X# , Dong LY# , Gai QJ ,  Ai WL , Wu Y , Xiao WC , Zhang J , An W.  Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway. Hepatol Commun . 2020 Jun 2;4(8):1149-1167. 

6. Zhang X, Zhan Y, Lin W, Zhao F, Guo C, Chen Y, Du M, Li D, Zhang L, An W#, Wang HR#, Xie P#. Smurf1 aggravates non-alcoholic fatty liver disease by stabilizing SREBP-1c in an E3 activity-independent manner. FASEB J . 2020 Jun;34(6):7631-7643.

7. Kong WN*, Li W*, Bai C, Dong Y, Wu Y, An W. Augmenter of liver regeneration-mediated mitophagy protects against hepatic ischemia/reperfusion injury. Am J Transplant. 2022 Jan;22(1):130-143.

8. Dong Y, Kong WN, An W. Downregulation of augmenter of liver regeneration impairs the therapeutic efficacy of liver epithelial progenitor cells against acute liver injury by enhancing mitochondrial fission. Stem Cells.  2021 Nov;39(11):1546-1562.

9. Zheng M, Ai Z, Guo Y, Chen Y, Xie P#, An W#. Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma. Oncogene. 2023 Jan;42(4):308-321.

10.Wang XL*, He JH*, Xie P, Wu Y, Dong LY, An W.Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic Steatosis. Cell Mol Gastroenterol Hepatol. 2025;19(3):101436.

Honors and Awards:

Received the Second Prize of Natural Science Award (Beijing Science and Technology Award) in 2022.

Won the Third Prize of Beijing Science and Technology Progress Award twice, in 2000 and 2002 respectively.

Former Chairperson of the Medical Cell Biology Branch of the Chinese Medical Association;
Former Acting Secretary-General and Standing Director of the Chinese Society of Anatomy;
Former Standing Director of the Chinese Society for Cell Biology;
Former Member of the Teaching Guidance Committee for Basic Medical Sciences under the Ministry of Education;
Former Member of the Basic Medical Sciences Discipline Review Group of the Academic Degrees Committee of the State Council;