Ping Xie

*：Co-first author; #：Co-corresponding author

[1] Liu F*, Liu W*, Tan Y*, Shang Y, Ling S, Jiang X, Zhang Z, Sun S, Xie P. PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer. Oncogene . 2025. 44(33):2997-3013

[2] Xu M, Liu W, Liu F, Xie P. Protein Neddylation beyond tumor cells is a vital modulator of anticancer immunity. Phenomics. 2025. In press.

[3] Zheng M, Ai Z, Guo Y, Chen Y, Xie P#, An W#. Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma. Oncogene . 2023. 42(4):308-321.

[4]Xie P*, #, Peng Z*, Chen Y, Li Y, Du M, Tan Y, Zhang X, Lu Z, Cui C, Liu C, He F, Zhang L#. Neddylation of PTEN regulates its nuclear import and promotes tumor development. Cell Research . 2021, 31(3): 291-311.

[5] Huang J*, Xie P*, Dong Y, An W. Inhibition of Drp1 SUMOylation by ALR protects the liver from ischemia-reperfusion injury. Cell Death & Differentiation. 2021; 28(4): 1174-1192.

[6] Du MG*, Liu F*, Chang Y*, Tong S, Liu W, Chen YJ, Xie P. Neddylation modification of the U3 snoRNA-binding protein RRP9 by Smurf1 promotes tumorigenesis. Journal of Biological Chemistry. 2021;297(5):101307.

[7] Li Y*, Xie P*, Lu L*, Wang J, Diao L, Liu Z, Guo F, He Y, Liu Y, Huang Q, Liang H, Li D#, He F#. An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network. Nature Communications. 2017. 8(1): 347.

[8] Xie P*, Zhang M*, He S*, Lu K, Chen Y, Xing G, Lu Y, Liu P, Li Y, Wang S, Chai N, Wu J, Deng H, Wang H, Cao Y, Zhao F, Cui Y, Wang J, He F, Zhang L. The Covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis. Nature Communications . 2014,5:3733.

[9] Miotto B*, Chibi M*, Xie P*, Koundrioukoff S, Moolman-Smook H, Pugh D, Debatisse M, He F, Zhang L#, Defossez PA#. The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability. Cell Reports . 2014, 7(2): 575-587.

Honors and Awards:

1. Beijing Science and Technology Award (Natural Science), Second Prize in 2022; Frist Prize in 2017 and 2014.

1. Standing Committee Member, Medical Cell Biology Society, Chinese Medical Association
2. Member, Cell Metabolism Branch, Chinese Society for Cell Biology (CSCB)
3. Member,Beijing Society for Cell Biology
4. Deputy Editor-in-Chief (Youth Editorial Board), Journal of Capital Medical University