*:Co-first author; #:Co-corresponding author
1.Wang Y, Zhang X, Qian S, Fang H, Wu X, Shen Y, Xu C, Zhang X, Jin X. Aging-induced episodic-like memory impairment could be alleviated by melatonin treatment via maintaining the integrity of blood-brain barrier and upregulating CRTC1. CNS Neuroscience & Therapeutics 2025 31(4):e70412
2.Zhang X, Du W, Qian S, Xu C, Jin X. Glial growth factor 2 treatment alleviates ischemia and reperfusion-compromised integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and YAP/TAZ-mediated paracellular permeability. 2024 Acta Pharmacologica Sinica 45(11):2241-2252
3.Hu X, Dong J, Geng P, Sun Y, Cheng H, Wang W, Jin X. Nicotine treatment alleviates acute ischemia stroke-compromised integrity of blood-brain barrier through regulating miR-21/Pdlim5. Translational Stroke Research 2024 15,672–687.
4.Wang X, Wang Q, Song M, Wang Y, Shen X, Ma C, Jin X# Chronic but not acute nicotine treatment ameliorates acute inflammation-induced working memory impairment by increasing CRTC1 and HCN2 in adult male mice. CNS Neuroscience & Therapeutics 2024 30(2):e14627
5.Wang Y, Du W, Hu X, Jin X # Wang W #. Targeting blood-brain barrier to delay aging-induced neurological diseases by modulating gut microbe, circadian rhythms and their interplays. Acta Pharmaceutica Sinica B 2023 13 (12), 4667-4687.
6.Wang Y, Du W, Sun Y, Hu X, Zhang J, Ma C, Jin X. CRTC1 is a potential target to delay aging-induced cognitive deficit by protecting the integrity of the blood-brain barrier via inhibiting inflammation. Journal of Cerebral Blood Flow and Metabolism 2023 43(7):1042-1059 Cover
7.Wang Q, Wang M, Sun Y, Hu X, Geng P, Shu H, Wang X, Zhang J, Cheng H, Wang W, X Jin. Nicotine pretreatment alleviates MK-801-induced behavioral and cognitive deficits in mice by regulating Pdlim5/CRTC1 in the PFC. Acta Pharmacologica Sinica 2023 44(4):780-790.
8.Shu H, Wang M, Song M, Sun Y, Shen X, Zhang J, and Jin X. Acute nicotine treatment alleviates LPS-induced impairment of fear memory reconsolidation through AMPK activation and CRTC1 upregulation in hippocampus. 2020 International Journal of Neuropsychopharmacology . 2020, 23(10):687-699.
9.Wang X, Xue G, Liu W, Shu H, Wang M, Sun Y, Li X, Sun Y, Liu C, Liu J, Liu W, X Jin. Melatonin alleviates lipopolysaccharide-compromised integrity of blood brain barrier by activation of AMP-activated protein kinase (AMPK) in old mice. Aging cell 2017, 16(2):414-421
10. Liu Y, Liu W, Sun Y, Shen X, Wang X, Pan R, Shu H, Liu C, Liu W, Liu K, X Jin. Normobaric hyperoxia extends neuro- and vaso-protection of N-Acetylcysteine in transient focal ischemia. Molecular Neurobiology 2017, 54:3418–3427