1. Suxin Li, Jianyi Lv, Zhihui Li, Qiuyu Zhang, Jing Lu, Xueyun Huo, Meng Guo, Xin Liu, Changlong Li, Jinghui Wang, Hanping Shi, Li Deng, Zhenwen Chen, and Xiaoyan Du* Overcoming Multi-Drug Resistance in SCLC: A Synergistic Approach with Venetoclax and Hydroxychloroquine Targeting the lncRNA LYPLAL1-DT/BCL2/BECN1 Pathway. Molecular Cancer, 2024, 23(1):243 DOI: 10.1186/s12943-024-02145-1
2. Hongjuan Fang#, Xiaohong Li#, Jianyi Lv, Xueyun Huo, Meng Guo, Xin Liu, Changlong Li, Zhenwen Chen, and Xiaoyan Du* Adipocytokines and Inflammation in Patients and a Gerbil Model: Implications for Obesity-Related and Nonobese Diabetes. Journal of Diabetes Research, 2024, https://doi.org/10.1155/2024/9683512
3. Guo Y, Cui Y, Sun M, Zhu X, Zhang Y, Lu J, Li C, Lv J, Guo M, Liu X, Chen Z, Du X*, Huo X*. Establishment and Application of a Novel Genetic Detection Panel for SNPs in Mongolian Gerbils. Genes (Basel), 2024, 5(6):817. doi: 10.3390/genes15060817. Jun 20
4. Wu Ying, Caijiao Hu, Zhihui Li, Feiyang Li, Jianyi Lv, Meng Guo, Xin Liu, Changlong Li, Xueyun Huo, Zhenwen Chen, Lifeng Yang, Xiaoyan Du*. Development of a new cerebral ischemia reperfusion model of Mongolian gerbils and standardized evaluation system. Anim Models Exp Med. 2024;7(1): 48-55.
5. Zhu Xiao, Wu Ying, Zhang Xing, Li Zhihui, Zhang Qiuyu, Hu Caijiao, Li Changlong, Hanping Shi, Li Deng, Chen Zhenwen, Ni Jianquan, Huo Xueyun*, Du Xiaoyan* Unexpected mutations occurred in CRISPRCas9 edited Drosophila analyzed by deeply whole genomic sequencing. Heliyon, 2024,10(7): e29061. doi: 10.1016/j.heliyon.2024.e29061.
6. Shuxin Li†, Jianyi Lv†, Xing Zhang†, Qiuyu Zhang, Zhihui Li, Jing Lu, Xueyun Huo, Meng Guo, Xin Liu, Ran Gao, Jianan Gong, Changlong Li, Weiying Li, Tongmei Zhang, Jinghui Wang, Zhenwen Chen*, and Xiaoyan Du*ELAVL4 Promotes the Tumorigenesis of Small Cell Lung Cancer by Stabilizing LncRNA LYPLAL1-DT and Enhancing Profilin2 Activation. FASEB J, 2023, 37(10): e23170. 7. Zhenkun Li†, Xueyun Huo†, Keyan Chen, Fenghua Yang, Weijiang Tan, Qi Zhang, Haixu Yu, Changlong Li, Deshan Zhou, Hao Chen, Baoquan Zhao, Yuan Wang, Zhenwen Chen* and Xiaoyan Du* Profilin 2 and Endothelial Exosomal Profilin 2 Promote Angiogenesis and Myocardial Infarction Repair in Mice. Frontiers in Cardiovascular Medicine, 2022, 9:781753. doi: 10.3389/fcvm.2022.781753.
8. Jianyi Lv, Yihan Liu, Jia Cui, Hongjuan Fang, Ying Wu, Xiao Zhu, Meng Guo, Changlong Li1, Jingtao Dou, Zhenwen Chen and Xiaoyan Du* Profile Screening of Differentially Expressed lncRNAs of Circulating Leukocytes in Type 2 Diabetes Patients and Differences From Type 1 Diabetes. Frontier in Endocrinology, 2022, 12:690555. doi: 10.3389/fendo.2021.690555
9. Xiao Zhu, Yihan Liu, Jia Cui, Jianyi Lv, Changlong Li, Jing Lu, Xueyun Huo, Jingtao Dou, Zhigang Bai, Zhenwen Chen and Xiaoyan Du.* LncRNA LYPLAL1-DT screening from type 2 diabetes with macrovascular complication contributes protective effects on human umbilical vein endothelial cells via regulating the miR-204-5p/SIRT1 axis. Cell Death Discovery, 2022, 8:245.
10. Yihan Liu, Xiaoming Du, Jia Cui, Changlong Li, Meng Guo, Jianyi Lv, Xin Liu, Jingtao Dou, Xiaoyan Du*, Hongjuan Fang* and Zhenwen Chen. A genome-wide analysis of long-noncoding RNAs in circulating leukocytes and their differential expression in type 1 diabetes patients. Journal of Diabetes Research, 2020, 2020: 9010314
Email：duduyan@ccmu.edu.cn
010-83950423 (lab)
Address：No.10, Xitoutiao, You’anmenwai, Beijing
Research Area：The Du laboratory focus on two scientific concerns. The first one is finding new therapeutic targets for cancer, diabetes, atherosclerosis, and heart failure, as well as the genetic molecular mechanism of these diseases. The second is Genetic Detection including genomic stability and Genetic monitoring.