*:Co-first author; #:Co-corresponding author
1.Jing Qu, Xiaoxi Ren, Fenqin Xue, Yi He, Ruihua Zhang, Yan Zheng, Haixia Huang, Wei Wang, Jianliang Zhang. Specific Knockdown of α-Synuclein by Peptide-Directed Proteasome Degradation Rescued Its Associated Neurotoxicity. Cell Chemical Biology, 2020, 27(6):751-762.
2.Xiaoxi Ren, Yun Zhao, Fenqin Xue, Yan Zheng, Haixia Huang, Wei Wang, Yongchang Chang, Hui Yang, Jianliang Zhang. Exosomal DNA Aptamer Targeting a-Synuclein Aggregates Reduced Neuropathological Deficits in a Mouse Parkinson’s Disease Model. Molecular Therapy-Nucleic Acids, 2019, 17:726-740.
3.Jing Qu, Hongxia Yan, Yuan Zheng, Fenqin Xue, Yan Zheng, Hongjuan Fang, Yongchang Chang, Hui Yang, Jianliang Zhang. The molecular mechanism of alpha-synuclein dependent regulation of protein Phosphatase 2A activity. Cellular Physiology and Biochemistry, 2018, 47(6): 2613-2625.
4.Yuan Zheng, Jing Qu, Fenqin Xue, Yan Zheng, Bo Yang, Yongchang Chang, Hui Yang, Jianliang Zhang. Novel DNA aptamers for Parkinson’s Disease treatment inhibit α-synuclein aggregation and facilitate its degradation. Molecular Therapy-Nucleic Acids, 2018, 11: 228-242.
5.Jing Qu, Shuqing Yu, Yuan Zheng, Yan Zheng, Hui Yang, Jianliang Zhang. Aptamer and its applications in neurodegenerative diseases. Cellular and Molecular Life Sciences, 2017, 74(4):683–695.
6.Junjun Zhao, Shuqing Yu, Yan Zheng, Hui Yang, Jianliang Zhang. Oxidative Modification and Its Implications for the Neurodegeneration of Parkinson’s Disease. Molecular Neurobiology, 2017, 54(2): 1404-1418.
7.Junjun Zhao, Yan Zheng, Fenqin Xue, Yongchang Chang, Hui Yang#, Jianliang Zhang#. Molecular basis of reactive oxygen species-induced inactivation of α4β2 nicotinic acetylcholine receptors. Free Radical Biology and Medicine, 2016, 97, 520-530.
8.Hongxia Yan, Na Pan, Fenqin Xue, Yan Zheng, Chaokun Li, Yongchang Chang, Zhiqing Xu, Hui Yang#, Jianliang Zhang#.The coupling interface and pore domain codetermine the single-channel activity of the a7 nicotinic receptor. Neuropharmacology, 2015, 95: 448-458.
9.Jianliang Zhang, Fenqin Xue, Yujun Liu, Hui Yang, Xiaomin Wang. The structural mechanism of the cys-loop receptor desensitization. Molecular Neurobiology, 2013, 48(1):97–108.
10.Jianliang Zhang, Fenqin Xue, Paul Whiteaker, Chaokun Li, Wen Wu, Benchang Shen, Yao Huang, Ronald J. Lukas, Yongchang Chang. Desensitization of α7 Nicotinic Receptor Is Governed by Coupling Strength Relative to Gate Tightness. Journal of Biological Chemistry, 2011, 286(28): 25331-25340.